Broncholaveolar lavage to detect cytomegalovirus infection, latency, and reactivation in immune competent hosts

Epigenetic Control of Cytomegalovirus Latency and Reactivation

Cytomegalovirus (CMV) gene expression is repressed in latency due to heterochromatinization of viral genomes. In murine CMV (MCMV) latently infected mice, viral genomes are bound to histones with heterochromatic modifications, to enzymes that mediate these modifications, and to adaptor proteins that may recruit co-repressor complexes. Kinetic analyses of repressor binding show that these repres...

Tuberculosis: latency and reactivation.

Intestinal Microsporidiosis in Iran (Kerman): Comparison in immune-compromised patients and immune competent people with diarrhea

Background and Purpose: Gastroenteritis and the clinical profile caused by Microsporidia, an opportunistic pathogen, may be severe in immunocompromised individuals, especially in AIDS patients. Conventionally, it is necessary to detect the small infective spores in stained smears. However, due to the limitations of the microscopy-based methods, several DNA-based methods such as polymerase cha...

Use of bronchoalveolar lavage to detect galactomannan for diagnosis of pulmonary aspergillosis among nonimmunocompromised hosts.

Pulmonary aspergillosis in nonimmunocompromised hosts, although rare, is being increasingly recognized. The diagnosis of pulmonary aspergillosis is difficult, since the recovery of Aspergillus from respiratory samples cannot differentiate colonization from invasion. We assessed the role of bronchoalveolar lavage (BAL) in detecting galactomannan (GM) for diagnosing pulmonary aspergillosis in 73 ...

Cytomegalovirus in Bronchoalveolar Lavage

public how to protect against 03. People whose 03 sensitivity is clinically apparent by symptoms or lung function loss are commonly advised to minimize exposure by avoiding outdoor exercise during pollution episodes. The same advice now seems appropriate for clinically "insensitive" individuals, given that they may experience asymptomatic lung function decrements, as well as lung inflammation a...